A system for multiattribute drug product comparison

Bruce L. Lambert*, Clement Yu, Mohanraj Thirumalai

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

We describe a system for multiattribute drug product searching. We then demonstrate the system's performance on sample queries, and evaluate the name-based similarity searching component. Ten drug names were used to query a database of existing drug names using five different retrieval methods. Retrieved names were merged into master lists and presented to 15 pharmacists. Pharmacists rated the similarity between the query name and each retrieved names on a scale of 1-5. We report the precision of our five different retrieval methods at 11 levels of recall. The best single measure was editex, with a precision of 17.4% averaged across 11 levels of recall. A regression model using four objective measures of similarity as predictors accounted for 40.6% of the variance in observed mean similarity ratings. Automated, multiattribute drug product searching may improve the effectiveness and efficiency of preapproval screening processes and thereby prevent medication errors.

Original languageEnglish (US)
Pages (from-to)31-56
Number of pages26
JournalJournal of Medical Systems
Volume28
Issue number2
StatePublished - Apr 1 2004

Keywords

  • Confusion
  • Dosage form
  • Dosing interval
  • Drug names
  • Information retrieval
  • Medication error
  • Precision
  • Recall
  • Route of administration
  • Similarity
  • Strength

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Information Systems
  • Health Informatics
  • Health Information Management

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