A unified view of propagating and localized surface plasmon resonance biosensors

Amanda J. Haes, Richard P. Van Duyne*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

588 Scopus citations


The intense colors of noble metal nanoparticles have inspired artists and fascinated scientists for hundreds of years. In this review, we describe refractive index sensing platforms based on the tunability of the localized surface plasmon resonance (LSPR) of arrays of silver nanoparticles and of single nanoparticles. Specifically, the color associated with single nanoparticles and surface-confined nanoparticle arrays will be shown to be tunable and useful as platforms for chemical and biological sensing. Finally, the LSPR nanosensor will be compared to traditional, flat surface, propagating surface plasmon resonance sensors.

Original languageEnglish (US)
Pages (from-to)920-930
Number of pages11
JournalAnalytical and Bioanalytical Chemistry
Issue number7-8
StatePublished - Aug 2004


  • Biosensing
  • Localized surface plasmon resonance
  • Nanosensor
  • Single nanoparticle
  • Spectroscopy

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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