Aberrant resting-state functional connectivity in a genetic rat model of depression

Kathleen A. Williams; Neha S. Mehta; Eva E. Redei; Lei Wang; Daniel Procissi

doi:10.1016/j.pscychresns.2014.02.001

Aberrant resting-state functional connectivity in a genetic rat model of depression

Kathleen A. Williams, Neha S. Mehta, Eva E. Redei^*, Lei Wang, Daniel Procissi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Abnormal intrinsic functional connectivity, measured by resting-state functional MRI, has been reported in major depressive disorder (MDD). Our study is the first to demonstrate hypo- and hyperconnectivity between the hippocampus and cortical, subcortical regions in a genetic animal model of depression, similar to connectivity anomalies found in MDD.

Original language	English (US)
Pages (from-to)	111-113
Number of pages	3
Journal	Psychiatry Research - Neuroimaging
Volume	222
Issue number	1-2
DOIs	https://doi.org/10.1016/j.pscychresns.2014.02.001
State	Published - Apr 30 2014

Keywords

Functional MRI
Hippocampus
Wistar Kyoto More Immobile

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.pscychresns.2014.02.001

Cite this

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abstract = "Abnormal intrinsic functional connectivity, measured by resting-state functional MRI, has been reported in major depressive disorder (MDD). Our study is the first to demonstrate hypo- and hyperconnectivity between the hippocampus and cortical, subcortical regions in a genetic animal model of depression, similar to connectivity anomalies found in MDD.",

keywords = "Functional MRI, Hippocampus, Wistar Kyoto More Immobile",

author = "Williams, {Kathleen A.} and Mehta, {Neha S.} and Redei, {Eva E.} and Lei Wang and Daniel Procissi",

note = "Funding Information: This study was supported by grants from the Davee Foundation. ",

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doi = "10.1016/j.pscychresns.2014.02.001",

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AU - Williams, Kathleen A.

AU - Mehta, Neha S.

AU - Redei, Eva E.

AU - Wang, Lei

AU - Procissi, Daniel

N1 - Funding Information: This study was supported by grants from the Davee Foundation.

PY - 2014/4/30

Y1 - 2014/4/30

N2 - Abnormal intrinsic functional connectivity, measured by resting-state functional MRI, has been reported in major depressive disorder (MDD). Our study is the first to demonstrate hypo- and hyperconnectivity between the hippocampus and cortical, subcortical regions in a genetic animal model of depression, similar to connectivity anomalies found in MDD.

AB - Abnormal intrinsic functional connectivity, measured by resting-state functional MRI, has been reported in major depressive disorder (MDD). Our study is the first to demonstrate hypo- and hyperconnectivity between the hippocampus and cortical, subcortical regions in a genetic animal model of depression, similar to connectivity anomalies found in MDD.

KW - Functional MRI

KW - Hippocampus

KW - Wistar Kyoto More Immobile

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JF - Psychiatry Research - Neuroimaging

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Aberrant resting-state functional connectivity in a genetic rat model of depression

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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