Aberrant resting-state functional connectivity in a genetic rat model of depression

Kathleen A. Williams, Neha S. Mehta, Eva E. Redei*, Lei Wang, Daniel Procissi

*Corresponding author for this work

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Abnormal intrinsic functional connectivity, measured by resting-state functional MRI, has been reported in major depressive disorder (MDD). Our study is the first to demonstrate hypo- and hyperconnectivity between the hippocampus and cortical, subcortical regions in a genetic animal model of depression, similar to connectivity anomalies found in MDD.

Original languageEnglish (US)
Pages (from-to)111-113
Number of pages3
JournalPsychiatry Research - Neuroimaging
Volume222
Issue number1-2
DOIs
StatePublished - Apr 30 2014

Keywords

  • Functional MRI
  • Hippocampus
  • Wistar Kyoto More Immobile

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health

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