Abnormalities in the Brain and Schizophrenia

T. J. Crow, Henry A. Nasrallah, Stephen C. Olson, Jeffrey A. Coffman, Steven B. Schwarzkopf, Paul Michael Ramirez, Lewis A. Opler, J. Daniel Kanofsky, Reuven Sandyk, Stanley R. Kay, Theodore Lidz, Stephen Fleck, Daniel R. Weinberger, Richard L. Suddath, E. Fuller Torrey, George W. Christison, Manual F. Casanova, M. Marsel Mesulam

Research output: Contribution to journalLetter

3 Scopus citations

Abstract

To the Editor: The study by Suddath et al. (March 22 issue)1 adds substantially to our knowledge of the nature of the brain changes in schizophrenia. However, neither that paper nor the editorial2 discussing its implications considers the possibility suggested by another recent study3 that the changes in schizophrenia reflect a primary disturbance of the determination of asymmetry. The findings of Suddath et al.1 are relevant. Whereas for a number of the comparisons between twins with schizophrenia and unaffected twins (e.g., volume measurements of the lateral ventricle and hippocampus) there are differences on both sides of the brain, for the…

Original languageEnglish (US)
Pages (from-to)545-548
Number of pages4
JournalNew England Journal of Medicine
Volume323
Issue number8
DOIs
StatePublished - Aug 23 1990

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Crow, T. J., Nasrallah, H. A., Olson, S. C., Coffman, J. A., Schwarzkopf, S. B., Ramirez, P. M., Opler, L. A., Kanofsky, J. D., Sandyk, R., Kay, S. R., Lidz, T., Fleck, S., Weinberger, D. R., Suddath, R. L., Torrey, E. F., Christison, G. W., Casanova, M. F., & Mesulam, M. M. (1990). Abnormalities in the Brain and Schizophrenia. New England Journal of Medicine, 323(8), 545-548. https://doi.org/10.1056/NEJM199008233230812