Absence of sperm-specific lactate dehydrogenase-x in patients with testis cancer

N. J. Vogelzang, P. H. Lange, E. Goldberg

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

LDH-x is a unique form of lactate dehydrogenase found in germinal epithelium during spermatogenesis. 53 patients with germ cell tumors were screened for the presence of LDH-x in the serum. No patient had detectable levels of the enzyme. 31 of the patients had elevated total serum LDH levels, and the isozyme fraction type 1 and/or type 2 was responsible for the elevation in all cases. LDH is a useful marker in germ cell tumors, but LDH-x is not the responsible isozyme.

Original languageEnglish (US)
Pages (from-to)269-272
Number of pages4
JournalOncodevelopmental Biology and Medicine
Volume3
Issue number4
StatePublished - Dec 1 1982

ASJC Scopus subject areas

  • Medicine(all)

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