Abundance of Repetitive Sequence Elements in the Mouse Testis-Specific Lactate Dehydrogenase-C Gene

Per G. Olsson, Hiroshi Tsujioka, Sonoko Narisawa, Erwin Goldberg, José Luis Millan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We have cloned and sequenced the entire mouse ldhc gene and mapped it physically in relation to the somatic ldha gene. The 2 genes were found to be oriented in head-to-tail fashion with about a 6-kilobase (kb) distance between the 3′ end of ldha and the 5′ end of ldhc. The ldhc gene is composed of 43% repetitive elements compared to only 16% in the ldha gene. Despite the close physical distance of mouse ldha and ldhc, the 2 genes have a very different content of repetitive elements, and this most likely reflects different levels of selective pressure.

Original languageEnglish (US)
Pages (from-to)918-920
Number of pages3
JournalJournal of andrology
Volume24
Issue number6
DOIs
StatePublished - 2003

Keywords

  • Isozyme
  • Restriction maps

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Reproductive Medicine
  • Endocrinology
  • Urology

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