Accelerated partial breast irradiation utilizing balloon brachytherapy techniques

Jonathan B. Strauss, Adam Dickler*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations


To overcome the barriers to BCT, methods of PBI in the setting of breast conservation have been explored. The method of PBI with the longest published follow-up is multi-catheter interstitial brachytherapy. Balloon-based brachytherapy with the MammoSite brachytherapy applicator was designed to simplify the brachytherapy procedure for PBI, enhance the reproducibility of the dosimetry, and improve patient comfort. The rates of local recurrence following PBI with the MammoSite applicator have been low, but there are few published reports and follow-up has been relatively short. The cosmetic outcomes and toxicity of MammoSite PBI are comparable to those seen after multicatheter-based PBI. Additional methods of balloon brachytherapy, including Xoft and SenoRx Contura have been developed. Finally, long-term follow-up after PBI is important for the welfare of individual patients and in order to establish the efficacy, late toxicity and cosmetic outcomes of this technique.

Original languageEnglish (US)
Pages (from-to)157-165
Number of pages9
JournalRadiotherapy and Oncology
Issue number2
StatePublished - May 2009


  • Accelerated partial breast irradiation
  • Brachytherapy
  • MammoSite

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Radiology Nuclear Medicine and imaging


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