Accelerating Food Allergy Research: Need for a Data Commons

Ruchi S. Gupta*, Shruti Sehgal, Mark Wlodarski, Lucy A. Bilaver, Firas H. Wehbe, Jonathan M. Spergel, Julie Wang, Christina E. Ciaccio, Sai R. Nimmagadda, Amal Assa'ad, Mahboobeh Mahdavinia, Richard L. Wasserman, Emily Brown, Scott H. Sicherer, J. Andrew Bird, Bruce Roberts, Hemant P. Sharma, Kenneth Mendez, Eleanor Garrow Holding, Lynda MitchellMark Corbett, Melanie Makhija, Justin B. Starren

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Food allergy is a significant health problem affecting approximately 8% of children and 11% of adults in the United States. It exhibits all the characteristics of a “complex” genetic trait; therefore, it is necessary to look at very large numbers of patients, far more than exist at any single organization, to eliminate gaps in the current understanding of this complex chronic disorder. Advances may be achieved by bringing together food allergy data from large numbers of patients into a Data Commons, a secure and efficient platform for researchers, comprising standardized data, available in a common interface for download and/or analysis, in accordance with the FAIR (Findable, Accessible, Interoperable, and Reusable) principles. Prior data commons initiatives indicate that research community consensus and support, formal food allergy ontology, data standards, an accepted platform and data management tools, an agreed upon infrastructure, and trusted governance are the foundation of any successful data commons. In this article, we will present the justification for the creation of a food allergy data commons and describe the core principles that can make it successful and sustainable.

Original languageEnglish (US)
Pages (from-to)1063-1067
Number of pages5
JournalJournal of Allergy and Clinical Immunology: In Practice
Issue number4
StatePublished - Apr 2023


  • Data Commons
  • Food allergy

ASJC Scopus subject areas

  • Immunology and Allergy


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