Acceptability, feasibility, and preliminary efficacy of a theorybased relational embodied conversational agent mobile phone intervention to promote HIV medication adherence in young hivpositive African American MSM

Mark S. Dworkin; Sangyoon Lee; Apurba Chakraborty; Colleen Monahan; Lisa Hightow-Weidman; Robert Garofalo; Dima M. Qato; Li Liu; Antonio Jimenez

doi:10.1521/aeap.2019.31.1.17

Acceptability, feasibility, and preliminary efficacy of a theorybased relational embodied conversational agent mobile phone intervention to promote HIV medication adherence in young hivpositive African American MSM

Mark S. Dworkin^*, Sangyoon Lee, Apurba Chakraborty, Colleen Monahan, Lisa Hightow-Weidman, Robert Garofalo, Dima M. Qato, Li Liu, Antonio Jimenez

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

An embodied conversational agent can serve as a relational agent and provide information, motivation, and behavioral skills. To evaluate the feasibility, acceptability, and preliminary efficacy of My Personal Health Guide, a theory-based mobile-delivered embodied conversational agent intervention to improve adherence to antiretroviral therapy in young African American men who have sex with men, we conducted this prospective pilot study using a 3-month pre-post design. Outcome measures included adherence, acceptability, feasibility, pre versus post health literacy, and pre versus post self-efficacy. There were 43 participants. Pill count adherence < 80% improved from 62% at baseline to 88% at follow-up (p = .05). The acceptability of the app was high. Feasibility issues identified included loss of usage data from unplanned participant app deletion. Health literacy improved whereas self-efficacy was high at baseline and follow-up. This pilot study of My Personal Health Guide demonstrated acceptability and preliminary efficacy in improving adherence in this important population.

Original language	English (US)
Pages (from-to)	17-37
Number of pages	21
Journal	AIDS Education and Prevention
Volume	31
Issue number	1
DOIs	https://doi.org/10.1521/aeap.2019.31.1.17
State	Published - Feb 2019

Funding

Mark S. Dworkin, Apurba Chakraborty, and Li Liu are affiliated with the Division of Epidemiology and Biostatistics,,University of Illinois at Chicago School of Public Health. Sangyoon Lee is affiliated with Connecticut College, New London, Connecticut. Colleen Monahan and Antonio Jimenez are affiliated with the University of Illinois at Chicago School of Public Health. Lisa Hightow-Weidman is affiliated with the University of North Carolina, Chapel Hill, North Carolina. Robert Garofalo is affiliated with the Department of Pediatrics, Northwestern University/Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, Illinois. Dima M. Qato is affiliated with the University of Illinois at Chicago College of Pharmacy, Chicago, Illinois. The authors thank the Community Outreach Intervention Project, including Mark Hartfield for assistance with recruitment and Eric Glenn of the Chicago Black Gay Men’s Caucus for consultation. This research was supported by the National Institute of Nursing Research of the National Institutes of Health under Award Number R21NR016420. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Address correspondence to Mark S. Dworkin, 1603 W. Taylor St. MC 923, Chicago, IL 60612. E-mail: [email protected]

Keywords

Adherence
African American MSM
Avatar
HIV
mhealth

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Dworkin, M. S., Lee, S., Chakraborty, A., Monahan, C., Hightow-Weidman, L., Garofalo, R., Qato, D. M., Liu, L., & Jimenez, A. (2019). Acceptability, feasibility, and preliminary efficacy of a theorybased relational embodied conversational agent mobile phone intervention to promote HIV medication adherence in young hivpositive African American MSM. AIDS Education and Prevention, 31(1), 17-37. https://doi.org/10.1521/aeap.2019.31.1.17

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abstract = "An embodied conversational agent can serve as a relational agent and provide information, motivation, and behavioral skills. To evaluate the feasibility, acceptability, and preliminary efficacy of My Personal Health Guide, a theory-based mobile-delivered embodied conversational agent intervention to improve adherence to antiretroviral therapy in young African American men who have sex with men, we conducted this prospective pilot study using a 3-month pre-post design. Outcome measures included adherence, acceptability, feasibility, pre versus post health literacy, and pre versus post self-efficacy. There were 43 participants. Pill count adherence < 80% improved from 62% at baseline to 88% at follow-up (p = .05). The acceptability of the app was high. Feasibility issues identified included loss of usage data from unplanned participant app deletion. Health literacy improved whereas self-efficacy was high at baseline and follow-up. This pilot study of My Personal Health Guide demonstrated acceptability and preliminary efficacy in improving adherence in this important population.",

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Dworkin, MS, Lee, S, Chakraborty, A, Monahan, C, Hightow-Weidman, L, Garofalo, R, Qato, DM, Liu, L & Jimenez, A 2019, 'Acceptability, feasibility, and preliminary efficacy of a theorybased relational embodied conversational agent mobile phone intervention to promote HIV medication adherence in young hivpositive African American MSM', AIDS Education and Prevention, vol. 31, no. 1, pp. 17-37. https://doi.org/10.1521/aeap.2019.31.1.17

Acceptability, feasibility, and preliminary efficacy of a theorybased relational embodied conversational agent mobile phone intervention to promote HIV medication adherence in young hivpositive African American MSM. / Dworkin, Mark S.; Lee, Sangyoon; Chakraborty, Apurba et al.
In: AIDS Education and Prevention, Vol. 31, No. 1, 02.2019, p. 17-37.

Research output: Contribution to journal › Article › peer-review

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AU - Hightow-Weidman, Lisa

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Dworkin MS, Lee S, Chakraborty A, Monahan C, Hightow-Weidman L, Garofalo R et al. Acceptability, feasibility, and preliminary efficacy of a theorybased relational embodied conversational agent mobile phone intervention to promote HIV medication adherence in young hivpositive African American MSM. AIDS Education and Prevention. 2019 Feb;31(1):17-37. doi: 10.1521/aeap.2019.31.1.17

Acceptability, feasibility, and preliminary efficacy of a theorybased relational embodied conversational agent mobile phone intervention to promote HIV medication adherence in young hivpositive African American MSM

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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