TY - JOUR
T1 - Access to technology and preferences for an mHealth intervention to promote medication adherence in pediatric acute lymphoblastic leukemia
T2 - Approach leveraging behavior change techniques
AU - Heneghan, Mallorie B.
AU - Hussain, Tasmeen
AU - Barrera, Leonardo
AU - Cai, Stephanie W.
AU - Haugen, Maureen
AU - Morgan, Elaine
AU - Rossoff, Jenna
AU - Weinstein, Joanna
AU - Hijiya, Nobuko
AU - Cella, David
AU - Badawy, Sherif M.
N1 - Funding Information:
This project was supported by grants from the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH) (K23HL150232) (PI: SB) and the Agency for Healthcare Research and Quality (AHRQ) (K12HS023011) (PI: SB). The project was also supported by the Northwestern University Clinical and Translational Sciences Institute (NUCATS) (PI: SB) through the National Institutes of Health’s National Center for Advancing Translational Sciences, UL1TR001422. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung, and Blood Institute (NHLBI), the National Institutes of Health (NIH), or the Agency for Healthcare Research and Quality (AHRQ).
Publisher Copyright:
© Mallorie B Heneghan, Tasmeen Hussain, Leonardo Barrera, Stephanie W Cai, Maureen Haugen, Elaine Morgan, Jenna Rossoff, Joanna Weinstein, Nobuko Hijiya, David Cella, Sherif M Badawy. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 18.02.2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)
PY - 2021/2
Y1 - 2021/2
N2 - Background: Suboptimal adherence to 6-mercaptopurine (6-MP) is prevalent in pediatric acute lymphoblastic leukemia (ALL) and associated with increased risk of relapse. Rapid uptake of personal technology makes mobile health (mHealth) an attractive platform to promote adherence. Objective: Study objectives were to examine access to mobile technology and preferences for an mHealth intervention to improve medication adherence in pediatric ALL. Methods: A cross-sectional survey was administered in oncology clinic to parents of children with ALL as well as adolescents and young adults (AYAs) with ALL receiving maintenance chemotherapy. Results: A total of 49 parents (median age [IQR] 39 [33-42] years; female 76% [37/49]) and 15 patients (median age [IQR] 17 [16-19]; male 80% [12/15]) participated. All parents and AYAs owned electronic tablets, smartphones, or both. Parents' most endorsed mHealth app features included a list of medications (71%, 35/49), information about 6-MP (71%, 35/49), refill reminders (71%, 35/49), and reminders to take 6-MP (71%, 35/49). AYAs' most endorsed features included refill reminders (73%, 11/15), reminders to take 6-MP (73%, 11/15), and tracking 6-MP (73%, 11/15). Conclusions: Parents and AYAs reported ubiquitous access to mobile technology and strong interest in multiple adherence-specific mHealth app features. Parents and AYAs provided valuable insight into preferred features for a multifunctional behavioral intervention (mHealth app) to promote medication adherence in pediatric ALL.
AB - Background: Suboptimal adherence to 6-mercaptopurine (6-MP) is prevalent in pediatric acute lymphoblastic leukemia (ALL) and associated with increased risk of relapse. Rapid uptake of personal technology makes mobile health (mHealth) an attractive platform to promote adherence. Objective: Study objectives were to examine access to mobile technology and preferences for an mHealth intervention to improve medication adherence in pediatric ALL. Methods: A cross-sectional survey was administered in oncology clinic to parents of children with ALL as well as adolescents and young adults (AYAs) with ALL receiving maintenance chemotherapy. Results: A total of 49 parents (median age [IQR] 39 [33-42] years; female 76% [37/49]) and 15 patients (median age [IQR] 17 [16-19]; male 80% [12/15]) participated. All parents and AYAs owned electronic tablets, smartphones, or both. Parents' most endorsed mHealth app features included a list of medications (71%, 35/49), information about 6-MP (71%, 35/49), refill reminders (71%, 35/49), and reminders to take 6-MP (71%, 35/49). AYAs' most endorsed features included refill reminders (73%, 11/15), reminders to take 6-MP (73%, 11/15), and tracking 6-MP (73%, 11/15). Conclusions: Parents and AYAs reported ubiquitous access to mobile technology and strong interest in multiple adherence-specific mHealth app features. Parents and AYAs provided valuable insight into preferred features for a multifunctional behavioral intervention (mHealth app) to promote medication adherence in pediatric ALL.
KW - Acute lymphoblastic leukemia
KW - Behavior change technique
KW - MHealth
KW - Medication adherence
KW - Oral chemotherapy
KW - Patient-centered
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UR - http://www.scopus.com/inward/citedby.url?scp=85101169088&partnerID=8YFLogxK
U2 - 10.2196/24893
DO - 10.2196/24893
M3 - Article
C2 - 33599621
AN - SCOPUS:85101169088
VL - 23
JO - Journal of Medical Internet Research
JF - Journal of Medical Internet Research
SN - 1439-4456
IS - 2
M1 - e24893
ER -