ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE)

Evan S. Dellon, Nirmala Gonsalves, Ikuo Hirano*, Glenn T. Furuta, Chris A. Liacouras, David A. Katzka

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

664 Scopus citations

Abstract

Esophageal eosinophilia and eosinophilic esophagitis (EoE) are increasingly recognized and prevalent conditions, which now represent common clinical problems encountered by gastroenterologists, pathologists, and allergists. The study of EoE has become a dynamic field with an evolving understanding of the pathogenesis, diagnosis, and treatment. Although there are limited data supporting management decisions, clinical parameters are needed to guide the care of patients with eosinophilic-esophageal disorders. In this evidence-based review, recommendations developed by adult and pediatric gastroenterologists are provided for the evaluation and management of these patients. New terminology is emphasized, particularly the concepts of esophageal eosinophilia and proton-pump inhibitor-responsive esophageal eosinophilia (PPI-REE) as entities distinct from EoE.

Original languageEnglish (US)
Pages (from-to)679-692
Number of pages14
JournalAmerican Journal of Gastroenterology
Volume108
Issue number5
DOIs
StatePublished - May 2013

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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