Achalasia is the best characterized and most readily treatable of the esophageal motor disorders. It provides an excellent example of a disease of the enteric nervous system in which there is degeneration of the myenteric neurons that normally innervate the lower esophageal sphincter (LES). Both the clinical manifestations and the therapies of achalasia focus on the integrity of the LES.
|Original language||English (US)|
|Number of pages||8|
|Journal||Clinical Perspectives in Gastroenterology|
|State||Published - Jan 1 2002|
ASJC Scopus subject areas