Active conductances in motoneuron dendrites enhance movement capabilities

Cj Heckman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Synaptic input to motoneurons was traditionally thought to flow passively from the dendrites to the soma and initial axon segment. It is now clear that voltage-sensitive channels in motoneuron dendrites can generate large active currents, which are influenced by neuromodulators that are released by brainstem neurons. These neuromodulators may be essential for generating large forces.

Original languageEnglish (US)
Pages (from-to)96-101
Number of pages6
JournalExercise and Sport Sciences Reviews
Volume31
Issue number2
DOIs
StatePublished - Apr 1 2003

Keywords

  • Monoamines
  • Motor unit
  • Neuromodulation
  • Persistent inward current
  • Synaptic input

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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