Activin signal transduction pathways

SA Pangas, TK Woodruff*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

151 Scopus citations

Abstract

Many of the signal transduction pathways required for mammalian endocrine cell function are conserved from flies and wormsThese model organisms permitted the illumination of the biological properties of ligands and provided systems in which cellular coactivating molecules could be identified rapidly. Our knowledge about the activin signaling components has been advanced tremendously by the work carried out in these systems. Subsequent research is beginning to reveal the complex interactions that serve to regulate this signaling pathway.

Original languageEnglish (US)
Pages (from-to)309-314
Number of pages6
JournalTrends in Endocrinology and Metabolism
Volume11
Issue number8
DOIs
StatePublished - 2000

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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