Acute exacerbation of interstitial lung disease after procedures

William H. Amundson, Emilian Racila, Tadashi Allen, H. Erhan Dincer, Rade Tomic, Maneesh Bhargava, David M. Perlman, Hyun Joo Kim*

*Corresponding author for this work

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Interstitial lung disease (ILD) is a category of diffuse parenchymal lung diseases characterized by inflammation and/or fibrosis. The best characterized ILD is idiopathic pulmonary fibrosis (IPF). Acute exacerbation of IPF is a dreaded occurrence with grim prognosis and suboptimal treatment options. There have been recent reports that acute exacerbation can occur in other ILDs (AE-ILD). Of note, some of these acute exacerbations follow lung procedures. This review summarizes the available information on AE-ILD and discusses the procedures reported to cause AE-ILD. We also discuss proposed mechanisms, risk factors, treatment and prognosis. This review should help to inform decision-making about risks versus benefits of procedures that are commonly recommended to diagnose ILD.

Original languageEnglish (US)
Pages (from-to)30-37
Number of pages8
JournalRespiratory Medicine
Volume150
DOIs
StatePublished - Apr 2019

Keywords

  • AE-ILD
  • Acute exacerbation
  • Acute exacerbation of interstitial lung disease
  • Interstitial lung disease
  • Lung biopsy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Amundson, W. H., Racila, E., Allen, T., Dincer, H. E., Tomic, R., Bhargava, M., Perlman, D. M., & Kim, H. J. (2019). Acute exacerbation of interstitial lung disease after procedures. Respiratory Medicine, 150, 30-37. https://doi.org/10.1016/j.rmed.2019.02.012