Acute Heart Failure Syndromes and Coronary Perfusion

Nirat Beohar*, Ata K. Erdogan, Daniel C. Lee, Hani N. Sabbah, Morton J. Kern, John Teerlink, Robert O. Bonow, Mihai Gheorghiade

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

44 Scopus citations


Acute heart failure syndromes (AHFS), with a high post-discharge mortality and rehospitalization rate, represent a significant public health burden. The treatment of patients hospitalized with AHFS often includes the use of vasoactive medications such as inotropes and vasodilators. Although such agents are frequently used, their safety and efficacy remain controversial. A significant number of patients with heart failure have underlying coronary artery disease and may be at greater risk from hemodynamic alterations that can diminish coronary perfusion. In AHFS, the relationship among vasoactive medications, coronary perfusion, and potential myocardial injury needs further investigation. Newer techniques now available to evaluate coronary perfusion should provide guidance for the evaluation of existing and future vasoactive therapies for AHFS.

Original languageEnglish (US)
Pages (from-to)13-16
Number of pages4
JournalJournal of the American College of Cardiology
Issue number1
StatePublished - Jul 1 2008


  • acute heart failure syndromes
  • coronary artery disease
  • coronary perfusion
  • microcirculation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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