Acute myocardial infarction, non‐bacterial thrombotic endocarditis, and disseminated intravascular coagulation in a severe hemophiliac

David Green*, Howard Snapper, Graziella Abu‐Jawdeh, Janardan K Reddy

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Thrombosis in hemophilia is very rare and is usually associated with the administration of prothrombin complex concentrates. We describe a severe hemophiliac with P. carinii pneumonia who had clinical and laboratory evidence of acute myocardial infarction and disseminated intravascular coagulation, and at autopsy, nonbacterial thrombotic endocarditis as well. We suggest that prothrombin complex concentrates should be used cautiously in the setting of acute infection, and perhaps be given with appropriate doses of anticoagulants such as heparin.

Original languageEnglish (US)
Pages (from-to)210-212
Number of pages3
JournalAmerican Journal of Hematology
Volume35
Issue number3
DOIs
StatePublished - Jan 1 1990

Keywords

  • AIDS
  • HIV infection
  • hemophilia B
  • non‐bacterial endocarditis

ASJC Scopus subject areas

  • Hematology

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