Acute Neurological Complications of Brain Tumors and Immune Therapies, a Guideline for the Neuro-hospitalist

Jigisha P. Thakkar*, Vikram C. Prabhu, Stasia Rouse, Rimas V. Lukas

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Purpose of Review: Patients with brain tumors presenting to the emergency room with acute neurologic complications may warrant urgent investigations and emergent management. As the neuro-hospitalist will likely encounter this complex patient population, an understanding of the acute neurologic issues will have value. Recent Findings: We discuss updated information and management regarding various acute neurologic complications among neuro-oncology patients and neurologic complications of immunotherapy. Summary: Understanding of the acute neurologic complications associated with central nervous system tumors and with common contemporary cancer treatments will facilitate the neuro-hospitalist management of these patient populations. While there are aspects analogous to the diagnosis and management in the non-oncologic population, a number of unique features discussed in this review should be considered.

Original languageEnglish (US)
Article number32
JournalCurrent neurology and neuroscience reports
Issue number8
StatePublished - Aug 1 2020


  • Brain metastases
  • Brain tumors
  • CART-T cell
  • Immunotherapies
  • Neurologic complications
  • Neurotoxicity

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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