Acute, posterior multifocal placoid pigment epitheliopathy: A case of 11 recurrences over 15 years

Liza M Cohen, Marion R. Munk, Debra A. Goldstein, Lee M. Jampol*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Purpose: To report the case of a patient with recurrent, acute posterior multifocal placoid pigment epitheliopathy. To the best of our knowledge, this is the longest documented course with the greatest number of recurrences reported. Methods: Observational case report of one patient. A 27-year-old otherwise healthy male patient presented with recurrence of new scotomata over 15 years. Fundus photography, fluorescein angiography, indocyanine green angiography, fundus autofluorescence, and optical coherence tomography documented his clinical course. Results: Over the course of 15 years, the patient developed 11 symptomatic (5 imaging-documented) recurrences of acute, posterior multifocal placoid pigment epitheliopathy affecting both eyes. Each episode manifested with new subjective scotomata and new lesions noted on imaging. Symptoms mostly resolved after each episode, and visual outcome remained excellent (20/20 in the right eye and 20/25 left eye at the last follow-up). Conclusion: Although typically monophasic, acute posterior multifocal placoid pigment epitheliopathy can rarely present with a recurrent course over a prolonged period of time and should be considered as a diagnosis in patients presenting with recurrent visual symptoms and new placoid lesions on imaging. In recurrent cases, visual recovery may still remain excellent.

Original languageEnglish (US)
Pages (from-to)226-230
Number of pages5
JournalRetinal Cases and Brief Reports
Volume9
Issue number3
DOIs
StatePublished - Jun 6 2015

Keywords

  • acute posterior multifocal placoid pigment epitheliopathy
  • placoid lesions
  • white spot syndromes

ASJC Scopus subject areas

  • Ophthalmology

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