Adenocarcinoma of the gastroesophageal junction after bariatric surgery

Laleh G. Melstrom*, David J. Bentrem, Michael J. Salvino, Matthew G. Blum, Mark S. Talamonti, Kenneth J. Printen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Background: The development of upper gastrointestinal malignancies after bariatric surgery has not been well characterized. Our objective was to review the experience of patients with distal esophageal cancer that was diagnosed after bariatric surgery. Methods: A retrospective review was conducted to identify patients who had undergone bariatric surgery (1999 to 2006) and who later developed high-grade dysplasia or adenocarcinoma of the distal esophagus. Results: Three patients (of 2,875 [0.1%]) developed esophageal cancer: 2 after Roux-en-Y gastric bypass and 1 after vertical banded gastroplasty. All three patients had complaints of reflux, and two were treated with esophagectomy. The third patient presented with invasive carcinoma and died 2 years after diagnosis. Conclusions: Our findings emphasize the importance of precise endoscopic evaluation before bariatric surgery in patients with gastroesophageal reflux disease (GERD), of the necessity for continuing postsurgical surveillance in patients with known Barrett's esophagitis, and of early evaluation in patients who develop new symptoms of GERD after bariatric surgery.

Original languageEnglish (US)
Pages (from-to)135-138
Number of pages4
JournalAmerican journal of surgery
Issue number1
StatePublished - Jul 2008


  • Adenocarcinoma
  • Bariatric surgery
  • Esophageal cancer
  • Gastroesophageal junction

ASJC Scopus subject areas

  • Surgery


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