Adherence, augmented adherence, and aggregation of polymorphonuclear leukocytes

J. J. McGillen*, J. P. Phair

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Adherence of polymorphonuclear leukocytes to nylon fiber was found to be plasma- independent and distinct from the processes of augmented adherence, leukocyte aggregation, and inhibition of random leukocyte migration, all of which are dependent on “activated” plasma. Nylon fibers were unable to “activate” plasma, in contrast to the complement-activating agent zymosan. Prior incubation of plasma with antiserum to the third component of complement (C3) inhibited aggregation of polymorphonuclear leukocytes by plasma incubated with zymosan, and heat-inactivation blocked.

Original languageEnglish (US)
Pages (from-to)69-73
Number of pages5
JournalJournal of Infectious Diseases
Volume139
Issue number1
DOIs
StatePublished - Jan 1979

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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