Abstract
Background: Sickle cell disease (SCD) patients have impaired domains of health-related quality of life (HRQOL). Hydroxyurea is safe and efficacious in SCD; however, adherence is suboptimal, and patients' perceptions are poorly understood amongst adolescents and young adults (AYA). Study objectives were to: (1) examine patients' perceptions of SCD and hydroxyurea; and (2) explore the relationship of their perceptions to clinical characteristics, HRQOL domains and hydroxyurea adherence. Methods: Thirty-four SCD patients on hydroxyurea (≥6 months) participated in a single-institution study. Study measures included Brief-Illness Perceptions Questionnaire,
Original language | English (US) |
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Article number | 136 |
Journal | Health and Quality of Life Outcomes |
Volume | 15 |
Issue number | 1 |
DOIs | |
State | Published - Jul 5 2017 |
Keywords
- Adherence
- Beliefs
- Health-related quality of life
- Hydroxyurea
- Patient reported outcomes
- Perceptions
- Sickle cell disease
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health