Abstract
Background: Sickle cell disease (SCD) patients have impaired domains of health-related quality of life (HRQOL). Hydroxyurea is safe and efficacious in SCD; however, adherence is suboptimal, and patients' perceptions are poorly understood amongst adolescents and young adults (AYA). Study objectives were to: (1) examine patients' perceptions of SCD and hydroxyurea; and (2) explore the relationship of their perceptions to clinical characteristics, HRQOL domains and hydroxyurea adherence. Methods: Thirty-four SCD patients on hydroxyurea (≥6 months) participated in a single-institution study. Study measures included Brief-Illness Perceptions Questionnaire,
| Original language | English (US) |
|---|---|
| Article number | 136 |
| Journal | Health and Quality of Life Outcomes |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 5 2017 |
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Keywords
- Adherence
- Beliefs
- Health-related quality of life
- Hydroxyurea
- Patient reported outcomes
- Perceptions
- Sickle cell disease
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
Cite this
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Adherence to hydroxyurea, health-related quality of life domains, and patients' perceptions of sickle cell disease and hydroxyurea : A cross-sectional study in adolescents and young adults. / Badawy, Sherif M; Thompson, Alexis A; Lai, Jin-Shei; Penedo, Frank J; Rychlik, Karen; Liem, Robert I.
In: Health and Quality of Life Outcomes, Vol. 15, No. 1, 136, 05.07.2017.Research output: Contribution to journal › Article
TY - JOUR
T1 - Adherence to hydroxyurea, health-related quality of life domains, and patients' perceptions of sickle cell disease and hydroxyurea
T2 - A cross-sectional study in adolescents and young adults
AU - Badawy, Sherif M
AU - Thompson, Alexis A
AU - Lai, Jin-Shei
AU - Penedo, Frank J
AU - Rychlik, Karen
AU - Liem, Robert I
PY - 2017/7/5
Y1 - 2017/7/5
N2 - Background: Sickle cell disease (SCD) patients have impaired domains of health-related quality of life (HRQOL). Hydroxyurea is safe and efficacious in SCD; however, adherence is suboptimal, and patients' perceptions are poorly understood amongst adolescents and young adults (AYA). Study objectives were to: (1) examine patients' perceptions of SCD and hydroxyurea; and (2) explore the relationship of their perceptions to clinical characteristics, HRQOL domains and hydroxyurea adherence. Methods: Thirty-four SCD patients on hydroxyurea (≥6 months) participated in a single-institution study. Study measures included Brief-Illness Perceptions Questionnaire,
AB - Background: Sickle cell disease (SCD) patients have impaired domains of health-related quality of life (HRQOL). Hydroxyurea is safe and efficacious in SCD; however, adherence is suboptimal, and patients' perceptions are poorly understood amongst adolescents and young adults (AYA). Study objectives were to: (1) examine patients' perceptions of SCD and hydroxyurea; and (2) explore the relationship of their perceptions to clinical characteristics, HRQOL domains and hydroxyurea adherence. Methods: Thirty-four SCD patients on hydroxyurea (≥6 months) participated in a single-institution study. Study measures included Brief-Illness Perceptions Questionnaire,
KW - Adherence
KW - Beliefs
KW - Health-related quality of life
KW - Hydroxyurea
KW - Patient reported outcomes
KW - Perceptions
KW - Sickle cell disease
UR - http://www.scopus.com/inward/record.url?scp=85021709604&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021709604&partnerID=8YFLogxK
U2 - 10.1186/s12955-017-0713-x
DO - 10.1186/s12955-017-0713-x
M3 - Article
VL - 15
JO - Health and Quality of Life Outcomes
JF - Health and Quality of Life Outcomes
SN - 1477-7525
IS - 1
M1 - 136
ER -