Adoptive immunotherapy of melanoma

Seth M. Pollack, Cassian Yee*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Adoptive immunotherapy involves the ex vivo manipulation and expansion of lymphocytes to treat cancer. These lymphocytes, or effector cells, are “adoptively” transferred into the recipient and may be infused alone or as part of a regimen that includes chemotherapy, radiation therapy, exogenous cytokines and/or other biologic agents (e.g., antibodies) designed to enhance their survival and killing potential in vivo.

Original languageEnglish (US)
Title of host publicationInnate Immune Regulation and Cancer Immunotherapy
PublisherSpringer New York
Pages439-465
Number of pages27
ISBN (Electronic)9781441999146
ISBN (Print)9781441999139
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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