Adult-Onset Atopic Dermatitis

Jonathan I. Silverberg*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


One in 4 adults with atopic dermatitis (AD) report adult-onset disease. Adult-onset AD appears to be associated with a different disease phenotype compared with childhood-onset AD. A broad differential diagnosis must be considered in a patient presenting with an adult-onset eczematous eruption, including allergic contact dermatitis, mycosis fungoides/cutaneous T-cell lymphoma, psoriasis, scabies, and so forth. This review will specifically address the diagnosis, workup, and management of adult-onset AD. In adults presenting a new-onset chronic eczematous eruption, consideration should be given to a diagnosis of adult-onset AD. Patch testing should be performed to rule out allergic contact dermatitis. A biopsy may be obtained to exclude alternative diagnoses, including cutaneous T-cell lymphoma and psoriasis.

Original languageEnglish (US)
Pages (from-to)28-33
Number of pages6
JournalJournal of Allergy and Clinical Immunology: In Practice
Issue number1
StatePublished - Jan 2019


  • Adult onset
  • Asthma
  • Atopic dermatitis
  • Eczema
  • Hay fever
  • Recurrent

ASJC Scopus subject areas

  • Immunology and Allergy


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