Abstract
Photodynamic therapy (PDT) based upon the use of light and photosensitizers (PSs) has been used as a novel treatment approach for a variety of tumors. It, however, has several major limitations in the clinic: poor water solubility, long-term phototoxicity, low tumor targeting efficacy, and limited light penetration. With advances in nanotechnology, materials science, and clinical interventional imaging procedures, various smart-PSs have been developed for improving their cancer-therapeutic efficacy while reducing the adverse effects. Here, we briefly review state-of-the-art smart-PSs and discuss the future directions of PDT technology.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 79-90 |
| Number of pages | 12 |
| Journal | Biomaterials Science |
| Volume | 6 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2018 |
ASJC Scopus subject areas
- Biomedical Engineering
- Materials Science(all)
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Cite this
Park, W., Cho, S., Han, J., Shin, H., Na, K., Lee, B., & Kim, D. H. (2018). Advanced smart-photosensitizers for more effective cancer treatment. Biomaterials Science, 6(1), 79-90. https://doi.org/10.1039/c7bm00872d