Abstract
Photodynamic therapy (PDT) based upon the use of light and photosensitizers (PSs) has been used as a novel treatment approach for a variety of tumors. It, however, has several major limitations in the clinic: poor water solubility, long-term phototoxicity, low tumor targeting efficacy, and limited light penetration. With advances in nanotechnology, materials science, and clinical interventional imaging procedures, various smart-PSs have been developed for improving their cancer-therapeutic efficacy while reducing the adverse effects. Here, we briefly review state-of-the-art smart-PSs and discuss the future directions of PDT technology.
Original language | English (US) |
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Pages (from-to) | 79-90 |
Number of pages | 12 |
Journal | Biomaterials Science |
Volume | 6 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2018 |
ASJC Scopus subject areas
- Biomedical Engineering
- Materials Science(all)