Abstract
The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale spatial atlas of the healthy human body at single-cell resolution by applying advanced technologies and disseminating resources to the community. As the HuBMAP moves past its first phase, creating ontologies, protocols and pipelines, this Perspective introduces the production phase: the generation of reference spatial maps of functional tissue units across many organs from diverse populations and the creation of mapping tools and infrastructure to advance biomedical research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1089-1100 |
| Number of pages | 12 |
| Journal | Nature Cell Biology |
| Volume | 25 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 2023 |
Funding
We thank L. M. McGuire, SciStories, F. Goncalves, H. Schlehlein and V. A. Deshpande for their efforts in designing and creating graphics. We thank A. Honkala for assistance with manuscript formatting. We thank Z. Galis from the National Heart, Lung, and Blood Institute for many useful comments. Support for title page creation and format was provided by AuthorArranger, a tool developed at the National Cancer Institute. The authors gratefully acknowledge NIH HuBMAP grants U54HL165442 and U01HL166058 (L.P.); U54DK134301 and OT2OD033753 (S.J.); U54EY032442, U54DK120058 and U54DK134302 (J.M.S.); OT2OD033756 and OT2OD026671 (K.B.); UH3CA246635 (N.L.K.); UG3CA256967 (H.L.); U54HG010426 (M.P.S.); UH3CA246633 (M.A.); U54HD104393 (L.C.L. and P.R.); U54DK127823 (E.S.N., J.P.C. and W.-J.Q.); OT2OD033758 (N.G.); UH3CA246594 (F.G.); U54EY032442 and U54DK134302 (J.P.G.); U54HL145611 (S.L. and Y.L.); U01HG012680 (A.N.); U54DK120058, U54EY032442 and U54DK134302 (B.R.S.); UG3CA256959 (M.Z.); and U54HL165440 (I.S.V.). The authors are also supported by these grants: 2U01DK114933, P50DK133943 and U24DK135157 (S.J.); U54HL145608 and U54HL165443 (J.S.H.); U24CA268108 and U2CDK114886 (K.B.); Department of Defense W81XWH-22-1-0058 and Additional Ventures (L.P.). J.W.H. was supported by an NIH T32 Fellowship (T32CA196585) and an American Cancer Society: Roaring Fork Valley Postdoctoral Fellowship (PF-20-032-01-CSM). This work was supported, in part, by the Intramural Research Program of the NIH, National Institute of Allergy and Infectious Diseases (NIAID) and National Cancer Institute (NCI) (A.J.R.). We thank L. M. McGuire, SciStories, F. Goncalves, H. Schlehlein and V. A. Deshpande for their efforts in designing and creating graphics. We thank A. Honkala for assistance with manuscript formatting. We thank Z. Galis from the National Heart, Lung, and Blood Institute for many useful comments. Support for title page creation and format was provided by AuthorArranger, a tool developed at the National Cancer Institute. The authors gratefully acknowledge NIH HuBMAP grants U54HL165442 and U01HL166058 (L.P.); U54DK134301 and OT2OD033753 (S.J.); U54EY032442, U54DK120058 and U54DK134302 (J.M.S.); OT2OD033756 and OT2OD026671 (K.B.); UH3CA246635 (N.L.K.); UG3CA256967 (H.L.); U54HG010426 (M.P.S.); UH3CA246633 (M.A.); U54HD104393 (L.C.L. and P.R.); U54DK127823 (E.S.N., J.P.C. and W.-J.Q.); OT2OD033758 (N.G.); UH3CA246594 (F.G.); U54EY032442 and U54DK134302 (J.P.G.); U54HL145611 (S.L. and Y.L.); U01HG012680 (A.N.); U54DK120058, U54EY032442 and U54DK134302 (B.R.S.); UG3CA256959 (M.Z.); and U54HL165440 (I.S.V.). The authors are also supported by these grants: 2U01DK114933, P50DK133943 and U24DK135157 (S.J.); U54HL145608 and U54HL165443 (J.S.H.); U24CA268108 and U2CDK114886 (K.B.); Department of Defense W81XWH-22-1-0058 and Additional Ventures (L.P.). J.W.H. was supported by an NIH T32 Fellowship (T32CA196585) and an American Cancer Society: Roaring Fork Valley Postdoctoral Fellowship (PF-20-032-01-CSM). This work was supported, in part, by the Intramural Research Program of the NIH, National Institute of Allergy and Infectious Diseases (NIAID) and National Cancer Institute (NCI) (A.J.R.).
ASJC Scopus subject areas
- Cell Biology