Advances in clinical staging, early intervention, and the prevention of psychosis

Tina Gupta, Vijay A. Mittal

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


The development of effective intervention and prevention strategies among individuals with psychosis risk syndromes may help to reduce symptomatology and conversion to a psychotic disorder. Although strides have been made in this area, more work is needed, particularly given the setbacks that remain (such as heterogeneity among this group). There has been a shift with the introduction of clinical staging models toward expanding current intervention and prevention efforts to a more developmental and transdiagnostic approach. With this, this article seeks to review treatments both recently and currently discussed in the staging literature, introduce advances in psychosis risk syndrome treatments that may be beneficial to consider in clinical staging heuristics, and pinpoint other promising options.

Original languageEnglish (US)
Article number2027
StatePublished - 2019


  • Psychosis Risk Syndromes; Psychosis; Clinical Staging; Intervention; Prevention

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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