Advances in the Evaluation and Management of Esophageal Disease of Systemic Sclerosis

Dustin A. Carlson*, Monique Hinchcliff, John E. Pandolfino

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations

Abstract

Symptoms of heartburn and dysphagia as well as objective findings of abnormal esophageal acid exposure and esophageal dysmotility are common in patients with systemic sclerosis (SSc). Treatments for SSc esophageal disease are generally limited to gastroesophageal reflux disease (GERD) treatment with proton pump inhibitors. Progresses made in esophageal diagnostic testing offer the potential for improved clinical characterization of esophageal disease in SSc that may help direct management decisions. In addition to reviewing GERD management in patients with SSc, present and potential uses of endoscopy, reflux monitoring, manometry, impedance planimetry, and endoscopic ultrasound are discussed.

Original languageEnglish (US)
JournalCurrent rheumatology reports
Volume17
Issue number1
DOIs
StatePublished - Jan 2015

Funding

This work was supported by RO1 DK079902 (J.E.P.) and T32 DK101363-01 (J.E.P) from the Public Health Service. It was also supported in part by an NIH-NIAMS K23 AR059763 (M.H.) and a research award from the Scleroderma Research Foundation (MH).

Keywords

  • Esophageal reflux monitoring
  • GERD
  • Impedance
  • Manometry
  • Systemic sclerosis

ASJC Scopus subject areas

  • Rheumatology

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