TY - JOUR
T1 - Advances on the Merger of Electrochemistry and Transition Metal Catalysis for Organic Synthesis
AU - Malapit, Christian A.
AU - Prater, Matthew B.
AU - Cabrera-Pardo, Jaime R.
AU - Li, Min
AU - Pham, Tammy D.
AU - McFadden, Timothy Patrick
AU - Blank, Skylar
AU - Minteer, Shelley D.
N1 - Funding Information:
We thank the support from the National Science Foundation Center for Synthetic Organic Electrochemistry (CHE-2002158). C.A.M. was supported by the National Institute of General Medical Sciences of the National Institutes of Health (K99GM140249).
Publisher Copyright:
© 2021 American Chemical Society.
PY - 2022/2/9
Y1 - 2022/2/9
N2 - Synthetic organic electrosynthesis has grown in the past few decades by achieving many valuable transformations for synthetic chemists. Although electrocatalysis has been popular for improving selectivity and efficiency in a wide variety of energy-related applications, in the last two decades, there has been much interest in electrocatalysis to develop conceptually novel transformations, selective functionalization, and sustainable reactions. This review discusses recent advances in the combination of electrochemistry and homogeneous transition-metal catalysis for organic synthesis. The enabling transformations, synthetic applications, and mechanistic studies are presented alongside advantages as well as future directions to address the challenges of metal-catalyzed electrosynthesis.
AB - Synthetic organic electrosynthesis has grown in the past few decades by achieving many valuable transformations for synthetic chemists. Although electrocatalysis has been popular for improving selectivity and efficiency in a wide variety of energy-related applications, in the last two decades, there has been much interest in electrocatalysis to develop conceptually novel transformations, selective functionalization, and sustainable reactions. This review discusses recent advances in the combination of electrochemistry and homogeneous transition-metal catalysis for organic synthesis. The enabling transformations, synthetic applications, and mechanistic studies are presented alongside advantages as well as future directions to address the challenges of metal-catalyzed electrosynthesis.
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U2 - 10.1021/acs.chemrev.1c00614
DO - 10.1021/acs.chemrev.1c00614
M3 - Review article
C2 - 34797053
AN - SCOPUS:85120378623
SN - 0009-2665
VL - 122
SP - 3180
EP - 3218
JO - Chemical Reviews
JF - Chemical Reviews
IS - 3
ER -