Affinity of thymic self-peptides for the TCR determines the selection of CD8⁺ T lymphocytes in the thymus

Keyphrases

• Thymus 100%
• Self-assembling Peptide 100%
• CD8+ T Lymphocytes 100%
• CD8+ T Cells 41%
• Positive Selection 25%
• Relative Affinity 16%
• Negative Selection 16%
• CD8+ Cells 16%
• Cell-based 8%
• Phosphorylation 8%
• High Affinity 8%
• Physiological Relevance 8%
• Thymic Selection 8%
• Thymocytes 8%
• Binding Affinity 8%
• Antigenic Peptide 8%
• Self-antigens 8%
• Low Affinity 8%
• High-affinity Binding 8%
• Developmental Fate 8%
• Cell Selection 8%
• MHC Class I 8%
• Fetal Thymus 8%
• TCR Complex 8%
• Medullary Thymic Epithelial Cells (mTECs) 8%
• Low-affinity Binding Sites 8%
• Thymocyte Development 8%
• Thymic Stromal Cells 8%
• Peptide-MHC Complex 8%
• Peptide Specificity 8%
• Synthetic Antigen 8%

Immunology and Microbiology

• Thymus 100%
• T Cell Receptor 100%
• CD8+ T Lymphocyte 100%
• CD8 50%
• Binding Affinity 30%
• Thymocyte 20%
• CD8+ Cell 20%
• Synthetic Antigen 10%
• Cell Selection 10%
• MHC Class I 10%