Air2Liquid Method for Selective, Sensitive Detection of Gas-Phase Organophosphates

Michael C. Brothers, Sungbong Kim, Doug Adkins, Pat Lewis, Joshua E. Smith, Diana Ostojich, Steve S. Kim, John A. Rogers, H. Mitchell Rubenstein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Environmental hazards typically are encountered in the gaseous phase; however, selective sensing modalities for identifying and quantitating compounds of interest in an inexpensive, pseudo-real-time format are severely lacking. Here, we present a novel proof-of-concept that combines an Air2Liquid sampler in conjunction with an oil-in-water microfluidic assay for detection of organophosphates. We believe this proof-of-concept will enable development of a new platform technology for semivolatile detection that we have demonstrated to detect 50 pmoles (2 ppb) of neurotoxic organophosphates.

Original languageEnglish (US)
Pages (from-to)13-18
Number of pages6
JournalACS Sensors
Issue number1
StatePublished - Jan 24 2020


  • gas sensor
  • microfluidic assay
  • organophosphate
  • selective sensor
  • semi-volatile detection

ASJC Scopus subject areas

  • Bioengineering
  • Instrumentation
  • Process Chemistry and Technology
  • Fluid Flow and Transfer Processes

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