Airway pressure release ventilation

M. C. Stock*, J. B. Downs

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


Airway pressure release ventilation (APRV) is a new mode of mechanical ventilation that allows unrestricted spontaneous ventilation during continuous positive airway pressure (CPAP) administration. APRV augments alveolar ventilation by briefly interrupting CPAP, thus allowing airway pressure and lung volume to fall - and then to rise when CPAP returns. This review describes animal and human investigation that demonstrates APRV's efficacy, some physiologic implications, and potential use for patients with acute lung injury - the population for whom it was designed.

Original languageEnglish (US)
Pages (from-to)217-224
Number of pages8
JournalProblems in Critical Care
Issue number2
StatePublished - 1990

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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