Allergic bronchopulmonary aspergillosis in cystic fibrosis

Peter Laufer, Jordan N. Fink*, W. Theodore Bruns, George F. Unger, John H. Kalbfleisch, Paul A. Greenberger, Roy Patterson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

163 Scopus citations

Abstract

One hundred patients with CF were screened for ABPA. Forty-eight male patients and 52 female patients with an age range of 2 to 34 yr (mean 14.2) were studied. Patients were evaluated for skin reactivity and serum precipitating antibodies to Af, predominant sputum organisms, total blood eosinophil levels, total serum IgE, and Af-specific IgE and IgG, as well as abnormalities of pulmonary function and chest x-ray films. Careful evaluation of all patients with CF demonstrated that 10% had features indicative of ABPA, which is another potentially destructive pulmonary disorder. Thus careful evaluation of patients with CF, especially those with asthma, may be rewarding in uncovering a disorder that may slow progression of CF when it is appropriately treated.

Original languageEnglish (US)
Pages (from-to)44-48
Number of pages5
JournalThe Journal of allergy and clinical immunology
Volume73
Issue number1 PART 1
DOIs
StatePublished - Jan 1984

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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