Allergic bronchopulmonary aspergillosis: Natural history and classification of early disease by serologic and roentgenographic studies

R. Patterson, Paul Allen Greenberger, J. M. Halwig, J. L. Liotta, M. Roberts

Research output: Contribution to journalArticlepeer-review

Abstract

Eighty-four patients with allergic bronchopulmonary aspergillosis (ABPA) were evaluated for a total of 294 patient-years with a mean observation period of 3.7 years and classified by the stage of ABPA. The largest percentage of patients were in the stage IV (corticosteriod-dependent asthma stage) group. The next largest percentage were in the stage V (fibrotic, end-stage lung disease) group. Of the latter 24 patients, eight had died. In addition, we describe 13 patients with all serologic characteristics of ABPA but without central bronchiectasis. We propose that theses patients have seropositive ABPA and represent the earliest cases of it that can be diagnosed in contrast with ABPA with central bronchiectasis in which lung damage is already present.

Original languageEnglish (US)
Pages (from-to)916-918
Number of pages3
JournalArchives of Internal Medicine
Volume146
Issue number5
DOIs
StatePublished - Jul 30 1986

ASJC Scopus subject areas

  • Internal Medicine

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