TY - JOUR
T1 - Allergic bronchopulmonary aspergillosis
T2 - Natural history and classification of early disease by serologic and roentgenographic studies
AU - Patterson, R.
AU - Greenberger, Paul Allen
AU - Halwig, J. M.
AU - Liotta, J. L.
AU - Roberts, M.
PY - 1986/7/30
Y1 - 1986/7/30
N2 - Eighty-four patients with allergic bronchopulmonary aspergillosis (ABPA) were evaluated for a total of 294 patient-years with a mean observation period of 3.7 years and classified by the stage of ABPA. The largest percentage of patients were in the stage IV (corticosteriod-dependent asthma stage) group. The next largest percentage were in the stage V (fibrotic, end-stage lung disease) group. Of the latter 24 patients, eight had died. In addition, we describe 13 patients with all serologic characteristics of ABPA but without central bronchiectasis. We propose that theses patients have seropositive ABPA and represent the earliest cases of it that can be diagnosed in contrast with ABPA with central bronchiectasis in which lung damage is already present.
AB - Eighty-four patients with allergic bronchopulmonary aspergillosis (ABPA) were evaluated for a total of 294 patient-years with a mean observation period of 3.7 years and classified by the stage of ABPA. The largest percentage of patients were in the stage IV (corticosteriod-dependent asthma stage) group. The next largest percentage were in the stage V (fibrotic, end-stage lung disease) group. Of the latter 24 patients, eight had died. In addition, we describe 13 patients with all serologic characteristics of ABPA but without central bronchiectasis. We propose that theses patients have seropositive ABPA and represent the earliest cases of it that can be diagnosed in contrast with ABPA with central bronchiectasis in which lung damage is already present.
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U2 - 10.1001/archinte.146.5.916
DO - 10.1001/archinte.146.5.916
M3 - Article
C2 - 3516103
SN - 0003-9926
VL - 146
SP - 916
EP - 918
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 5
ER -