Allergic reactions to streptokinase consistent with anaphylactic or antigen-antibody complex-mediated damage

Kris G. McGrath; Barry Zeffren; Jay Alexander; Kerry Kaplan; Roy Patterson

doi:10.1016/0091-6749(85)90726-2

Allergic reactions to streptokinase consistent with anaphylactic or antigen-antibody complex-mediated damage

Kris G. McGrath, Barry Zeffren, Jay Alexander, Kerry Kaplan, Roy Patterson^*

^*Corresponding author for this work

Medicine, Allergy Division

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

Streptokinase used as a thrombolytic agent may produce immunologic drug reactions. We report a second case of IgE-mediated anaphylaxis and a late reaction to streptokinase. This late reaction was consistent with an IgG-mediated antigen-antibody disease with transient renal involvement, fever, and cutaneous lesions. The second case responded to prednisone therapy.

Original language	English (US)
Pages (from-to)	453-457
Number of pages	5
Journal	The Journal of allergy and clinical immunology
Volume	76
Issue number	3
DOIs	https://doi.org/10.1016/0091-6749(85)90726-2
State	Published - Sep 1985

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1016/0091-6749(85)90726-2

Cite this

@article{941645a16f5c439ebecf1241ea56c3cf,

title = "Allergic reactions to streptokinase consistent with anaphylactic or antigen-antibody complex-mediated damage",

abstract = "Streptokinase used as a thrombolytic agent may produce immunologic drug reactions. We report a second case of IgE-mediated anaphylaxis and a late reaction to streptokinase. This late reaction was consistent with an IgG-mediated antigen-antibody disease with transient renal involvement, fever, and cutaneous lesions. The second case responded to prednisone therapy.",

author = "McGrath, {Kris G.} and Barry Zeffren and Jay Alexander and Kerry Kaplan and Roy Patterson",

year = "1985",

month = sep,

doi = "10.1016/0091-6749(85)90726-2",

language = "English (US)",

volume = "76",

pages = "453--457",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Mosby Inc.",

number = "3",

}

TY - JOUR

T1 - Allergic reactions to streptokinase consistent with anaphylactic or antigen-antibody complex-mediated damage

AU - McGrath, Kris G.

AU - Zeffren, Barry

AU - Alexander, Jay

AU - Kaplan, Kerry

AU - Patterson, Roy

PY - 1985/9

Y1 - 1985/9

N2 - Streptokinase used as a thrombolytic agent may produce immunologic drug reactions. We report a second case of IgE-mediated anaphylaxis and a late reaction to streptokinase. This late reaction was consistent with an IgG-mediated antigen-antibody disease with transient renal involvement, fever, and cutaneous lesions. The second case responded to prednisone therapy.

AB - Streptokinase used as a thrombolytic agent may produce immunologic drug reactions. We report a second case of IgE-mediated anaphylaxis and a late reaction to streptokinase. This late reaction was consistent with an IgG-mediated antigen-antibody disease with transient renal involvement, fever, and cutaneous lesions. The second case responded to prednisone therapy.

UR - http://www.scopus.com/inward/record.url?scp=0022000796&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022000796&partnerID=8YFLogxK

U2 - 10.1016/0091-6749(85)90726-2

DO - 10.1016/0091-6749(85)90726-2

M3 - Article

C2 - 3928729

AN - SCOPUS:0022000796

VL - 76

SP - 453

EP - 457

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

SN - 0091-6749

IS - 3

ER -

Allergic reactions to streptokinase consistent with anaphylactic or antigen-antibody complex-mediated damage

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this