Allogroups of rabbit Ig heavy chains

S. Dray, B. S. Kim, A. Gilman Sachs

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Genes controlling rabbit immunoglobulin heavy chains are the V(H)a, V(H)x, and V(H)y genes for the variable regions and C(γ)de, C(α)f, C(α)g and C(γ)n for the constant regions. These genes are closely linked. In family studies, using allotypic specificities as the genetic markers, at least 6 haploid sets of these genes have been found to cosegregate as Mendelian units and are called allogroups. The recognition of these allogroups is important for studies of antibody diversity and the chromosomal mapping of immunoglobulin genes.

Original languageEnglish (US)
Pages (from-to)41-47
Number of pages7
Volume125 C
Issue number1-2
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Medicine(all)


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