Altruistic decisions following penetrating traumatic brain injury

Jorge Moll, Ricardo De Oliveira-Souza*, Rodrigo Basilio, Ivanei Edson Bramati, Barry Gordon, Geraldine Rodríguez-Nieto, Roland Zahn, Frank Krueger, Jordan Henry Grafman

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The cerebral correlates of altruistic decisions have increasingly attracted the interest of neuroscientists. To date, investigations on the neural underpinnings of altruistic decisions have primarily been conducted in healthy adults undergoing functional neuroimaging as they engaged in decisions to punish third parties. The chief purpose of the present study was to investigate altruistic decisions following focal brain damage with a novel altruistic decision task. In contrast to studies that have focused either on altruistic punishment or donation, the Altruistic Decision Task allows players to anonymously punish or donate to 30 charitable organizations involved with salient societal issues such as abortion, nuclear energy and civil rights. Ninety-four Vietnam War veterans with variable patterns of penetrating traumatic brain injury and 28 healthy veterans who also served in combat participated in the study as normal controls. Participants were asked to invest $1 to punish or reward real societal organizations, or keep the money for themselves. Associations between lesion distribution and performance on the task were analysed with multivariate support vector regression, which enables the assessment of the joint contribution of multiple regions in the determination of a given behaviour of interest. Our main findings were: (i) bilateral dorsomedial prefrontal lesions increased altruistic punishment, whereas lesions of the right perisylvian region and left temporo-insular cortex decreased punishment; (ii) altruistic donations were increased by bilateral lesions of the dorsomedial parietal cortex, whereas lesions of the right posterior superior temporal sulcus and middle temporal gyri decreased donations; (iii) altruistic punishment and donation were only weakly correlated, emphasizing their dissociable neuroanatomical associations; and (iv) altruistic decisions were not related to post-traumatic personality changes. These findings indicate that altruistic punishment and donation are determined by largely non-overlapping cerebral regions, which have previously been implicated in social cognition and moral experience such as evaluations of intentionality and intuitions of justice and morality. 10.1093/brain/awy064-video1 awy064media1 5758316955001

Original languageEnglish (US)
Pages (from-to)1558-1569
Number of pages12
JournalBrain
Volume141
Issue number5
DOIs
StatePublished - May 1 2018

Fingerprint

Penetrating Head Injuries
Punishment
Veterans
Temporal Lobe
Organizations
Nuclear Energy
Intuition
Civil Rights
Parietal Lobe
Functional Neuroimaging
Vietnam
Brain
Social Justice
Task Performance and Analysis
Reward
Cerebral Cortex
Cognition
Personality
Traumatic Brain Injury

Keywords

  • altruism
  • costly donation
  • costly punishment
  • penetrating traumatic brain injury
  • selfishness

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Moll, J., De Oliveira-Souza, R., Basilio, R., Bramati, I. E., Gordon, B., Rodríguez-Nieto, G., ... Grafman, J. H. (2018). Altruistic decisions following penetrating traumatic brain injury. Brain, 141(5), 1558-1569. https://doi.org/10.1093/brain/awy064
Moll, Jorge ; De Oliveira-Souza, Ricardo ; Basilio, Rodrigo ; Bramati, Ivanei Edson ; Gordon, Barry ; Rodríguez-Nieto, Geraldine ; Zahn, Roland ; Krueger, Frank ; Grafman, Jordan Henry. / Altruistic decisions following penetrating traumatic brain injury. In: Brain. 2018 ; Vol. 141, No. 5. pp. 1558-1569.
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Moll, J, De Oliveira-Souza, R, Basilio, R, Bramati, IE, Gordon, B, Rodríguez-Nieto, G, Zahn, R, Krueger, F & Grafman, JH 2018, 'Altruistic decisions following penetrating traumatic brain injury', Brain, vol. 141, no. 5, pp. 1558-1569. https://doi.org/10.1093/brain/awy064

Altruistic decisions following penetrating traumatic brain injury. / Moll, Jorge; De Oliveira-Souza, Ricardo; Basilio, Rodrigo; Bramati, Ivanei Edson; Gordon, Barry; Rodríguez-Nieto, Geraldine; Zahn, Roland; Krueger, Frank; Grafman, Jordan Henry.

In: Brain, Vol. 141, No. 5, 01.05.2018, p. 1558-1569.

Research output: Contribution to journalArticle

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Moll J, De Oliveira-Souza R, Basilio R, Bramati IE, Gordon B, Rodríguez-Nieto G et al. Altruistic decisions following penetrating traumatic brain injury. Brain. 2018 May 1;141(5):1558-1569. https://doi.org/10.1093/brain/awy064