Ambulatory pH monitoring: New advances and indications

Brant Lutsi, Ikuo Hirano*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Ambulatory pH monitoring is currently used to objectively demonstrate abnormal degrees of esophageal acid exposure in patients with suspected gastroesophageal reflux disease. The development of wireless pH capsule recording has improved the tolerability and increased the duration of pH recording. Use of symptom-reflux correlation measures and pH testing, combining periods off and on PPI therapy, serves to optimize the performance of conventional pH testing. On the other hand, devices that measure bile reflux as well as nonacid reflux (esophageal impedance testing) have broadened the definition of gastroesophageal reflux and present potential explanations for patients with continued symptoms despite high-dose PPI therapy. These advances and their current and future clinical applications are reviewed.

Original languageEnglish (US)
Pages (from-to)835-842
Number of pages8
JournalGastroenterology and Hepatology
Issue number11
StatePublished - Nov 1 2006


  • Bilitec
  • Chest pain
  • Gastroesophageal reflux disease
  • Impedance
  • Laryngitis
  • Ph monitoring

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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