Aminocaproic Acid Decreases Secondary Hemorrhage After Traumatic Hyphema

John J. Mcgetrick; Lee M. Jampol; Morton F. Goldberg; Marcel Frenkel; Richard G. Fiscella

doi:10.1001/archopht.1983.01040020033003

Aminocaproic Acid Decreases Secondary Hemorrhage After Traumatic Hyphema

John J. Mcgetrick, Lee M. Jampol, Morton F. Goldberg, Marcel Frenkel, Richard G. Fiscella

Ophthalmology

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Forty-eight patients (49 eyes) had nonperforating traumatic hyphema. Twenty-eight patients (28 eyes with hyphema) received oral aminocaproic acid, an antifibrinolytic agent, in a dosage of 100 mg/kg every four hours for five days, up to a maximum daily dose of 30 g. Twenty patients (21 eyes with hyphema) received placebo in an identical regimen. One eye treated with aminocaproic acid rebled; seven eyes receiving the placebo rebled. The results of this study show a statistically significant reduction in the incidence of secondary hemorrhage in the patients receiving aminocaproic acid.

Original language	English (US)
Pages (from-to)	1031-1033
Number of pages	3
Journal	Archives of ophthalmology
Volume	101
Issue number	7
DOIs	https://doi.org/10.1001/archopht.1983.01040020033003
State	Published - Jul 1983

ASJC Scopus subject areas

Ophthalmology

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title = "Aminocaproic Acid Decreases Secondary Hemorrhage After Traumatic Hyphema",

abstract = "Forty-eight patients (49 eyes) had nonperforating traumatic hyphema. Twenty-eight patients (28 eyes with hyphema) received oral aminocaproic acid, an antifibrinolytic agent, in a dosage of 100 mg/kg every four hours for five days, up to a maximum daily dose of 30 g. Twenty patients (21 eyes with hyphema) received placebo in an identical regimen. One eye treated with aminocaproic acid rebled; seven eyes receiving the placebo rebled. The results of this study show a statistically significant reduction in the incidence of secondary hemorrhage in the patients receiving aminocaproic acid.",

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AU - Fiscella, Richard G.

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AB - Forty-eight patients (49 eyes) had nonperforating traumatic hyphema. Twenty-eight patients (28 eyes with hyphema) received oral aminocaproic acid, an antifibrinolytic agent, in a dosage of 100 mg/kg every four hours for five days, up to a maximum daily dose of 30 g. Twenty patients (21 eyes with hyphema) received placebo in an identical regimen. One eye treated with aminocaproic acid rebled; seven eyes receiving the placebo rebled. The results of this study show a statistically significant reduction in the incidence of secondary hemorrhage in the patients receiving aminocaproic acid.

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Aminocaproic Acid Decreases Secondary Hemorrhage After Traumatic Hyphema

Abstract

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