Global left ventricular diastolic filling is often abnormal in resting patients with coronary artery disease (CAD). However, abnormalities in the amount (in contrast to rate) of early global filling have not yet been established in CAD patients with normal, resting systolic function, i. e. , normal wall motion and normal resting ejection fraction. The authors compare the amount of early filling in normal, resting subjects with the amount of early filling observed in patients having CAD with normal and, for control purposes, abnormal resting, systolic function. When considered by group, the mean amount of early ventricular filling is reduced (P<. 001) in patients having CAD with, or without, evidence of systolic dysfunction. However, when resting systolic function is normal, the frequency of this abnormality is low (27% of patients) and rises to encompass the majority of patients (61%) only when systolic function at rest is abnormal.