Amyotrophic lateral sclerosis presenting with a clivus mass and dysarthria

Nicholas J. Maragakis*, Andrea C. Pardo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A patient developed dysarthria and was found to have fibrous dysplasia of the clivus accompanied by cranial nerve impingement, particularly the hypoglossal canal. The dysarthria progressed to more severe bulbar dysfunction and a subsequent diagnosis of amyotrophic lateral sclerosis. This case highlights a discussion of the potential influences of focal lesions on the site of symptom onset in this neurodegenerative disease.

Original languageEnglish (US)
Pages (from-to)80-82
Number of pages3
JournalJournal of Clinical Neuromuscular Disease
Issue number2
StatePublished - Dec 2006


  • Dysarthria
  • Dysphagia
  • Fibrous dysplasia
  • Neurodegeneration

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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