An efficient and possibly general packing mode for crystals of B-DNA oligonucleotides

George Minasov, Valya Tereshko, Boris Chernov, Lucy Malinina*

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Two crystal forms of the self-complementary deoxytetramer GpGpCpC have been obtained by use of the phase diagram technique: hexagonal P6222 or P6422 with a = b = 67.7 Å, c = 105.6 Å, and trigonal P3212 or P3112 with a = b = 116.9 Å, c = 116.4 Å. Diffraction patterns from both crystals show strong 3.38 Å reflections that are typical of base-stacking in B-DNA. The self-rotation function R(φ, ψ, 180°) for the hexagonal form exhibits peaks representing pseudodyad rotation, whose periodicity also suggests B-DNA. Crystal packing arguments also favor use of this crystal form for a B helix.

Original languageEnglish (US)
Pages (from-to)136-143
Number of pages8
JournalJournal of Crystal Growth
Volume122
Issue number1-4
DOIs
StatePublished - Aug 2 1992

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Inorganic Chemistry
  • Materials Chemistry

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