An Epstein-Barr virus DNA fragment encodes messages for the two major envelope glycoproteins (gp350/300 and gp220/200)

M. Hummel, D. Thorley Lawson, E. Kieff

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

The genes encoding the two major Epstein-Barr virus glycoproteins (gp350/300 and gp220/200) have been mapped to a 5-kilobase fragment of the viral genome (BamHI-L). This fragment encodes 3.4- and 2.8-kilobase RNAs which translate proteins of 135 and 100 kilodaltons, respectively. Both proteins react with antiserum specific for gp350/300 and gp220/200. The 135-kilodalton protein is identical in size to the nascent polypeptide precursor to gp350/300, and the 100-kilodalton protein is the expected size of the polypeptide precursor to gp220/200.

Original languageEnglish (US)
Pages (from-to)413-417
Number of pages5
JournalJournal of virology
Volume49
Issue number2
DOIs
StatePublished - 1984

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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