An examination of content overlap and disorder-specific predictions in the associations of neuroticism with anxiety and depression

Amanda A. Uliaszek*, Katherina K. Hauner, Richard E Zinbarg, Michelle G. Craske, Susan Mineka, James W Griffith, Raphael D. Rose

*Corresponding author for this work

Research output: Contribution to journalArticle

48 Scopus citations


This study examines whether content overlap artificially inflates estimates of the associations of emotional disorders with neuroticism and whether disorder-specificity of prediction exists. We demonstrated a statistical approach for testing the validity of hypothesized facets of neuroticism. In a sample of 627 adolescents, we indentified six facets of neuroticism, one intermediate facet, and a general neuroticism factor (GNF). Only the GNF and the depression facet were significantly associated with depressive symptomatology. The GNF and all facets significantly predicted anxiety symptomatology. This study offers a new statistical approach for addressing content overlap, testing for disorder-specific prediction and identifying facets of a broad personality trait, while indicating that content overlap does not largely explain the associations of neuroticism with psychopathology.

Original languageEnglish (US)
Pages (from-to)785-794
Number of pages10
JournalJournal of Research in Personality
Issue number5
StatePublished - Oct 1 2009



  • Anxiety disorders
  • Depression
  • Neuroticism
  • Structural equation modeling

ASJC Scopus subject areas

  • Social Psychology
  • Psychology(all)

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