An exploration of relative health stock in advanced cancer patients

Darrell J. Gaskin*, Kevin P. Weinfurt, Liana D. Castel, Venita DePuy, Yun Li, Andrew Balshem, Al B Benson III, Caroline B. Burnett, Sandra Corbett, John Marshall, Elyse Slater, Daniel P. Sulmasy, David Van Echo, Neal J. Meropol, Kevin A. Schulman

*Corresponding author for this work

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Objective. The authors sought to empirically test whether relative health stock, a measure of patients' sense of loss in their health due to illness, influences the treatment decisions of patients facing life-threatening conditions. Specifically, they estimated the effect of relative health stock on advanced cancer patients' decisions to participate in phase I clinical trials. Method. A multicenter study was conducted to survey 328 advanced cancer patients who were offered the opportunity to participate in phase I trials. The authors asked patients to estimate the probabilities of therapeutic benefits and toxicity, their relative health stock, risk preference, and the importance of quality of life. Results. Controlling for health-related quality of life, an increase in relative health stock by 10 percentage points reduced the odds of choosing to participate in a phase I trial by 16% (odds ratio = 0.84, 95% confidence interval = 0.72, 0.97). Conclusion. Relative health stock affects advanced cancer patients' treatment decisions.

Original languageEnglish (US)
Pages (from-to)614-624
Number of pages11
JournalMedical Decision Making
Volume24
Issue number6
DOIs
StatePublished - Nov 1 2004

Keywords

  • Cancer
  • Clinical trials
  • Decision making
  • Patient preferences
  • Phase I trials

ASJC Scopus subject areas

  • Health Policy

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    Gaskin, D. J., Weinfurt, K. P., Castel, L. D., DePuy, V., Li, Y., Balshem, A., Benson III, A. B., Burnett, C. B., Corbett, S., Marshall, J., Slater, E., Sulmasy, D. P., Van Echo, D., Meropol, N. J., & Schulman, K. A. (2004). An exploration of relative health stock in advanced cancer patients. Medical Decision Making, 24(6), 614-624. https://doi.org/10.1177/0272989X04271041