An exploratory analysis of the impact of family functioning on treatment for depression in adolescents

Norah C. Feeny; Susan G. Silva; Mark A. Reinecke; Steven McNulty; Robert L. Findling; Paul Rohde; John F. Curry; Golda S. Ginsburg; Christopher J. Kratochvil; Sanjeev M. Pathak; Diane E. May; Betsy D. Kennard; Anne D. Simons; Karen C. Wells; Michele Robins; David Rosenberg; John S. March

doi:10.1080/15374410903297148

An exploratory analysis of the impact of family functioning on treatment for depression in adolescents

Norah C. Feeny, Susan G. Silva, Mark A. Reinecke, Steven McNulty, Robert L. Findling, Paul Rohde, John F. Curry, Golda S. Ginsburg, Christopher J. Kratochvil, Sanjeev M. Pathak, Diane E. May, Betsy D. Kennard, Anne D. Simons, Karen C. Wells, Michele Robins, David Rosenberg, John S. March

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

This article explores aspects of family environment and parent-child conflict that may predict or moderate response to acute treatments among depressed adolescents (N=439) randomly assigned to fluoxetine, cognitive behavioral therapy, their combination, or placebo. Outcomes were Week 12 scores on measures of depression and global impairment. Of 20 candidate variables, one predictor emerged: Across treatments, adolescents with mothers who reported less parent-child conflict were more likely to benefit than their counterparts. When family functioning moderated outcome, adolescents who endorsed more negative environments were more likely to benefit from fluoxetine. Similarly, when moderating effects were seen on cognitive behavioral therapy conditions, they were in the direction of being less effective among teens reporting poorer family environments.

Original language	English (US)
Pages (from-to)	814-825
Number of pages	12
Journal	Journal of Clinical Child and Adolescent Psychology
Volume	38
Issue number	6
DOIs	https://doi.org/10.1080/15374410903297148
State	Published - 2009

Funding

ASJC Scopus subject areas

Clinical Psychology
Developmental and Educational Psychology

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Feeny, N. C., Silva, S. G., Reinecke, M. A., McNulty, S., Findling, R. L., Rohde, P., Curry, J. F., Ginsburg, G. S., Kratochvil, C. J., Pathak, S. M., May, D. E., Kennard, B. D., Simons, A. D., Wells, K. C., Robins, M., Rosenberg, D., & March, J. S. (2009). An exploratory analysis of the impact of family functioning on treatment for depression in adolescents. Journal of Clinical Child and Adolescent Psychology, 38(6), 814-825. https://doi.org/10.1080/15374410903297148

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abstract = "This article explores aspects of family environment and parent-child conflict that may predict or moderate response to acute treatments among depressed adolescents (N=439) randomly assigned to fluoxetine, cognitive behavioral therapy, their combination, or placebo. Outcomes were Week 12 scores on measures of depression and global impairment. Of 20 candidate variables, one predictor emerged: Across treatments, adolescents with mothers who reported less parent-child conflict were more likely to benefit than their counterparts. When family functioning moderated outcome, adolescents who endorsed more negative environments were more likely to benefit from fluoxetine. Similarly, when moderating effects were seen on cognitive behavioral therapy conditions, they were in the direction of being less effective among teens reporting poorer family environments.",

author = "Feeny, {Norah C.} and Silva, {Susan G.} and Reinecke, {Mark A.} and Steven McNulty and Findling, {Robert L.} and Paul Rohde and Curry, {John F.} and Ginsburg, {Golda S.} and Kratochvil, {Christopher J.} and Pathak, {Sanjeev M.} and May, {Diane E.} and Kennard, {Betsy D.} and Simons, {Anne D.} and Wells, {Karen C.} and Michele Robins and David Rosenberg and March, {John S.}",

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Feeny, NC, Silva, SG, Reinecke, MA, McNulty, S, Findling, RL, Rohde, P, Curry, JF, Ginsburg, GS, Kratochvil, CJ, Pathak, SM, May, DE, Kennard, BD, Simons, AD, Wells, KC, Robins, M, Rosenberg, D & March, JS 2009, 'An exploratory analysis of the impact of family functioning on treatment for depression in adolescents', Journal of Clinical Child and Adolescent Psychology, vol. 38, no. 6, pp. 814-825. https://doi.org/10.1080/15374410903297148

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An exploratory analysis of the impact of family functioning on treatment for depression in adolescents

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