An integrative model of subcortical auditory plasticity

Bharath Chandrasekaran*, Erika Skoe, Nina Kraus

*Corresponding author for this work

Research output: Contribution to journalReview article

26 Scopus citations

Abstract

In direct conflict with the concept of auditory brainstem nuclei as passive relay stations for behaviorally-relevant signals, recent studies have demonstrated plasticity of the auditory signal in the brainstem. In this paper we provide an overview of the forms of plasticity evidenced in subcortical auditory regions. We posit an integrative model of auditory plasticity, which argues for a continuous, online modulation of bottom-up signals via corticofugal pathways, based on an algorithm that anticipates and updates incoming stimulus regularities. We discuss the negative implications of plasticity in clinical dysfunction and propose novel methods of eliciting brainstem responses that could specify the biological nature of auditory processing deficits.

Original languageEnglish (US)
Pages (from-to)539-552
Number of pages14
JournalBrain Topography
Volume27
Issue number4
DOIs
StatePublished - Jul 2014

Keywords

  • ABR
  • Auditory
  • Plasticity
  • Predictive coding
  • Stimulus-specific adaptation

ASJC Scopus subject areas

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

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