An international co-operative study on the relation of blood pressure to electrolyte excretion in populations. I. design and methods

Geofferey Rose*, Jeremiah Stamler, Rose Stembler, Paul Elliott, Michael Marmot, Kalevi Pyôrâlà, Hugo Kesteloot, Joseph Joossens, Lennart Hansson, Guiseppe Mancia, Alan Dyer, Susana Sans, Daan Kromhout, Ulrich Laaser, The INTERSALT Co-Operative Research Group

*Corresponding author for this work

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

INTERSALT is a collaborative study of the relationship between blood pressure and sodium and potassium intake in more than 50 population samples from 32 countries, representing a wide range of sodium intakes. The study uses standardized techniques for blood pressure measurement, collection of 24-h and spot urine samples, and recording the major confounding variables. Investigators, who have been trained at regional meetings, follow rigorous quality control checks. Laboratory work and data analysis are all conducted centrally. This report presents the study design and methods.

Original languageEnglish (US)
Pages (from-to)781-787
Number of pages7
JournalJournal of hypertension
Volume4
Issue number6
DOIs
StatePublished - Dec 1986

Keywords

  • Blood pressure
  • Population differences
  • Potassium excretion
  • Sodium excretion

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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    Rose, G., Stamler, J., Stembler, R., Elliott, P., Marmot, M., Pyôrâlà, K., Kesteloot, H., Joossens, J., Hansson, L., Mancia, G., Dyer, A., Sans, S., Kromhout, D., Laaser, U., & The INTERSALT Co-Operative Research Group (1986). An international co-operative study on the relation of blood pressure to electrolyte excretion in populations. I. design and methods. Journal of hypertension, 4(6), 781-787. https://doi.org/10.1097/00004872-198612000-00014