An Investigation of narrative ability in Boys with Autism and fragile X syndrome

Abigail L. Hogan-Brown*, Molly Losh, Gary E. Martin, Deborah J. Mueffelmann

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Whereas pragmatic language difficulties are characteristic of both autism and Fragile X syndrome, it is unclear whether such deficits are qualitatively similar or whether certain skills are differentially affected. This study compared narrative competence in boys with autism, Fragile X syndrome, Down syndrome, and typical development. Results revealed that an interaction between diagnosis and nonverbal mental age predicted narrative microstructure (e.g., complex syntax) but not macrostructure (e.g., thematic maintenance). Correlations with FMR1-related variation were investigated in children with Fragile X syndrome. While CGG repeat length was associated with many language characteristics, nonverbal IQ appeared to mediate these relationships. These findings are an important step toward understanding narrative abilities in boys with and without the FMR1 mutation.

Original languageEnglish (US)
Pages (from-to)77-94
Number of pages18
JournalAmerican Journal on Intellectual and Developmental Disabilities
Volume118
Issue number2
DOIs
StatePublished - Mar 2013

Keywords

  • Autism
  • Down syndrome
  • FMR1
  • Fragile X syndrome
  • Mental age
  • Narrative

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Psychiatry and Mental health

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