An old drug for new ideas: Metformin promotes adult neurogenesis and spatial memory formation

Matthew B. Potts; Daniel A. Lim

doi:10.1016/j.stem.2012.06.003

An old drug for new ideas: Metformin promotes adult neurogenesis and spatial memory formation

Matthew B. Potts, Daniel A. Lim^*

^*Corresponding author for this work

Neurological Surgery

Research output: Contribution to journal › Short survey › peer-review

50 Scopus citations

Abstract

Identifying well-tolerated, oral medications that enhance adult neurogenesis is of great clinical interest. In this issue of Cell Stem Cell, Wang et al. (2012) demonstrate that the diabetes medication metformin enhances spatial learning in mice by activating the atypical PKC/CBP pathway in adult neural stem cells.

Original language	English (US)
Pages (from-to)	5-6
Number of pages	2
Journal	Cell stem cell
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2012.06.003
State	Published - Jul 6 2012

ASJC Scopus subject areas

Genetics
Molecular Medicine
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.stem.2012.06.003

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title = "An old drug for new ideas: Metformin promotes adult neurogenesis and spatial memory formation",

abstract = "Identifying well-tolerated, oral medications that enhance adult neurogenesis is of great clinical interest. In this issue of Cell Stem Cell, Wang et al. (2012) demonstrate that the diabetes medication metformin enhances spatial learning in mice by activating the atypical PKC/CBP pathway in adult neural stem cells.",

author = "Potts, {Matthew B.} and Lim, {Daniel A.}",

year = "2012",

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T2 - Metformin promotes adult neurogenesis and spatial memory formation

AU - Potts, Matthew B.

AU - Lim, Daniel A.

PY - 2012/7/6

Y1 - 2012/7/6

N2 - Identifying well-tolerated, oral medications that enhance adult neurogenesis is of great clinical interest. In this issue of Cell Stem Cell, Wang et al. (2012) demonstrate that the diabetes medication metformin enhances spatial learning in mice by activating the atypical PKC/CBP pathway in adult neural stem cells.

AB - Identifying well-tolerated, oral medications that enhance adult neurogenesis is of great clinical interest. In this issue of Cell Stem Cell, Wang et al. (2012) demonstrate that the diabetes medication metformin enhances spatial learning in mice by activating the atypical PKC/CBP pathway in adult neural stem cells.

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U2 - 10.1016/j.stem.2012.06.003

DO - 10.1016/j.stem.2012.06.003

M3 - Short survey

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AN - SCOPUS:84863617404

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JO - Cell stem cell

JF - Cell stem cell

IS - 1

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An old drug for new ideas: Metformin promotes adult neurogenesis and spatial memory formation

Abstract

ASJC Scopus subject areas

UN SDGs

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